Gene description for B2M
Gene name	beta-2-microglobulin
Gene symbol	B2M
Other names/aliases	IMD43
Species	Homo sapiens
Experiment description of studies that identified B2M in Leukemia cells
1 Experiment ID 253 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Radioimmunoassay PubMed ID 9126269    Organism Homo sapiens Experiment description Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Authors Bess JW Jr, Gorelick RJ, Bosche WJ, Henderson LE, Arthur LO Journal name Virology Publication year 1997 Sample Leukemia cells Sample name CEM-SS - HIV non infected Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.08-1.29 g/mL Molecules identified in the study Protein Methods used in the study Radioimmunoassay EV-TRACK -
2 Experiment ID 254 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Radioimmunoassay PubMed ID 9126269    Organism Homo sapiens Experiment description Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Authors Bess JW Jr, Gorelick RJ, Bosche WJ, Henderson LE, Arthur LO Journal name Virology Publication year 1997 Sample Leukemia cells Sample name CEM-SS - HIV infected Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.08-1.29 g/mL Molecules identified in the study Protein Methods used in the study Radioimmunoassay EV-TRACK -
3 Experiment ID 257 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Radioimmunoassay PubMed ID 9126269    Organism Homo sapiens Experiment description Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Authors Bess JW Jr, Gorelick RJ, Bosche WJ, Henderson LE, Arthur LO Journal name Virology Publication year 1997 Sample Leukemia cells Sample name MOLT-3 - HIV non infected Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.08-1.29 g/mL Molecules identified in the study Protein Methods used in the study Radioimmunoassay EV-TRACK -
4 Experiment ID 258 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Radioimmunoassay PubMed ID 9126269    Organism Homo sapiens Experiment description Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Authors Bess JW Jr, Gorelick RJ, Bosche WJ, Henderson LE, Arthur LO Journal name Virology Publication year 1997 Sample Leukemia cells Sample name MOLT-3 - HIV infected Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.08-1.29 g/mL Molecules identified in the study Protein Methods used in the study Radioimmunoassay EV-TRACK -
5 Experiment ID 602 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Leukemia cells Sample name CCRF-CEM Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
6 Experiment ID 1250 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24939845    Organism Homo sapiens Experiment description Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Authors Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F. Journal name J Biol Chem. Publication year 2014 Sample Leukemia cells Sample name MT2 - HTLV-1 infected Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140028: EV-METRIC:33%
7 Experiment ID 1251 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24939845    Organism Homo sapiens Experiment description Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Authors Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F. Journal name J Biol Chem. Publication year 2014 Sample Leukemia cells Sample name ED-40515 -HTLV-1 infected Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140028: EV-METRIC:33%